The Department of Chemistry at Saint Joseph’s University is a community - of faculty, staff, students and alumni - dedicated to excellence in education in general and excellence in chemical education in particular.

The Department offers not only courses in the traditional major areas of chemistry, but also in interdisciplinary areas, such as biochemistry, biophysical chemistry, bioinorganic chemistry, environmental chemistry, environmental geochemistry, and organometallic chemistry. Just as importantly, the department has an active summer research program, in which faculty and undergraduate researchers work together to investigate problems of current interest.

We encourage our students to become involved in faculty-directed independent research projects during both the academic year and the summer. Gifts from our alumni and local industry and research grants to our faculty members from federal agencies and private foundations provide the financial support for this work. Our students regularly publish their results in scientific journals and make presentations at regional and national meetings at which they have been given recognition and won awards.

Our curriculum prepares our graduates to choose a wide range of career paths, and our graduates have pursued graduate study in chemistry or biochemistry; professional degrees in the health sciences; graduate studies in other fields (including business, law, theater, etc.); and direct employment after graduation.

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Submissions from 2017

On the Importance of Electronic Symmetry for Triplet State Delocalization, Paul Joseph Angiolillo

Submissions from 2014

Heme Peripheral Groups Interactions in Extremely Low-Dielectric Constant Media and Their Contributions to the Heme Reduction Potential, Jose F. Cerda

Submissions from 2013

A Three-Dimensional Printed Cell for Rapid, Low-Volume Spectroelectrochemistry, Jose F. Cerda

Electrochemical Determination of Heme-Linked pKas and the Importance of Using Fluoride Binding in Heme Proteins, Jose F. Cerda

Spectroelectrochemical Measurements of Redox Proteins by Using a Simple UV/Visible Cell, Jose F. Cerda

Synthesis of Tungsten and Molybdenum Carbon Dioxide Complexes, Peter Michael Graham

Zinc Supplementation Modifies Tight Junctions and Alters Barrier Function of CACO-2 Human Intestinal Epithelial Layers, E. Peter Zurbach

Submissions from 2012

Manipulating Reduction Potentials in an Artificial Safranin Cofactor, Jose F. Cerda

Submissions from 2011

An Electrochemical Method That Can Be Used for Probing the Interactions between a Fluoride- Heme Bound Ion and the Distal Residues in Heme Proteins, Jose F. Cerda

Application of an Electrochemical Method That Can Be Used to Probe the Distal Residues in Heme Proteins to Elucidate Their Roles in Oxygen Binding and Reduction, Jose F. Cerda

Electrochemical and Structural Coupling of the Naphthoquinone Amino Acid, Jose F. Cerda

Electrochemical Method used for Probing the Interactions between Distal Residues and a Heme Bound Fluoride, Jose F. Cerda

Electrochemical Method used for Probing the Interactions between Distal Residues and a Heme Bound Fluoride, Jose F. Cerda

Reaction of 4,5-diiodopentacyclo[4.3.0.02,4.03,8.05,7]nonane, Mark A. Forman

Reductive dehalogenation of 4,5-diiodopentacyclo[4.3.0.02,4.03,8.05,7]nonane: Cyclobutane dimers, Mark A. Forman

Synthesis of Tungsten and Molybdenum Complexes for the Activation of Carbon Dioxide, Peter Michael Graham

Acid Rain-Induced Weathering of Limestone Monuments, Usha Rao

Metal Concentrations in Pennsylvania's Rivers, Usha Rao

The Presence of Metals in the Dissolved and Sedimentary Fractions of the Susquehanna-Lackawanna River System of Pennsylvania, Usha Rao

The Presence of Metals in the Dissolved and Sedimentary Fractions of the Susquehanna-Lackawanna River System of Pennsylvania, Usha Rao

The Presence of Metals in the Dissolved and Sedimentary Fractions of the Susquehanna-Lackawanna River System of Pennsylvania, Usha Rao

In Vivo Self-hydroxylation of an Iron-substituted Manganese-dependent Extradiol Cleaving Catechol Dioxygenase, Mark F. Reynolds

Spectroscopic and Site-directed Mutagenesis Studies of Conserved Residues in the Heme Domain, Mark F. Reynolds

Submissions from 2010

Experiences as an Assistant Professor in Chemistry, Jose F. Cerda

Pentacyclo[4.3.0.02,4.03,8.05,7]non-4-ene: Alternative synthetic approaches, Mark A. Forman

Synthetic approaches to 4-iodo-5-(trimethylsilyl)pentacyclo[4.3.0.02,4.03,8.05,7]nonane using functionalized organometallics, Mark A. Forman

Hydroperoxide-Initiated Intramolecular Insertions of NO into Metal−Carbon Bonds, Peter Michael Graham

Conserved F-helix Residues Play an Important Role in the Oxygen Sensing Mechanism of the heme-PAS SmFixL protein from Sinorhizobium meliloti, Mark F. Reynolds

Conserved F-helix Residues Play an Important Role in the Oxygen Sensing Mechanism of the heme-PAS SmFixL protein from Sinorhizobium meliloti, Mark F. Reynolds

Conserved F-helix Residues Play an Important Role in the Oxygen Sensing Mechanism of the heme-PAS SmFixL protein from Sinorhizobium meliloti, Mark F. Reynolds

Ethics in Chemistry: It Begins with You, Jean M. Smolen

Origins and Futures of Common Chemicals and Their Effect on the Environment, Jean M. Smolen

Omeprazole induces gastric transmucosal permeability to the peptide bradykinin, E. Peter Zurbach

Submissions from 2009

Reversible Proton Coupled Electron Transfer in a Peptide-incorporated Naphthoquinone Amino Acid, Jose F. Cerda

Reversible Proton Coupled Electron Transfer in a Peptide-incorporated Naphthoquinone Amino Acid, Jose F. Cerda

New Synthetic Approaches Toward Pentacyclo[4.3.0.02,4.03,8.05,7]non-4-ene, Mark A. Forman

Progress Toward the Synthesis of 4-Iodo-5-(trimethylsilyl)pentacyclo[4.3.0.02,4.03,8.05,7]nonane, Mark A. Forman

Progress Toward the Synthesis of 4-Iodo-5-(trimethylsilyl)pentacyclo[4.3.0.02,4.03,8.05,7]nonane, Mark A. Forman

Toward Alkane Functionalization Effected with Cp*W(NO)(alkyl)(η3-allyl) Complexes, Peter Michael Graham

The Presence of Metals in the Susquehanna-Lackawanna Watershed: The Legacy of 150 Years of Coal Mining, Usha Rao

The Presence of Metals in the Susquehanna-Lackawanna Watershed: The Legacy of 150 Years of Coal Mining, Usha Rao

Conserved Falpha-helix Residues Play an Important Role in the Oxygen Sensing Mechanism of the heme-PAS SmFixL protein from Sinorhizobium meliloti, Mark F. Reynolds

Role of Conserved Falpha-helix Residues in the Native Fold and Stability of the Kinase-Inhibited Oxy State of the Oxygen-sensing FixL Protein from Sinorhizobium meliloti. Archives of Biochemistry and Biophysics 2009, 485, 150-159., Mark F. Reynolds

Role of Conserved Fα-helix Residues in the Native Fold and Stability of the Kinase-Inhibited Oxy State of the Oxygen Sensing FixL Protein from Sinorhizobium meliloti, Mark F. Reynolds

Role of Conserved Fα-helix Residues in the Native Fold and Stability of the Kinase-Inhibited Oxy State of the Oxygen Sensing FixL Protein from Sinorhizobium meliloti, Mark F. Reynolds

Role of Conserved Fα-helix Residues in the Native Fold and Stability of the Kinase-Inhibited Oxy State of the Oxygen Sensing FixL Protein from Sinorhizobium meliloti, Mark F. Reynolds

Submissions from 2008

Dielectric and thermal properties of some supercooled alkyl halides, John G. Berberian

Hydrogen Bond-free Flavin Redox Properties: Managing Flavins in Extreme Aprotic Solvents, Jose F. Cerda

Hydrogen Bond-free Flavin Redox Properties: Managing Flavins in Extreme Aprotic Solvents, Jose F. Cerda

Reversible Proton Coupled Electron Transfer in a Peptide-incorporated Naphthoquinone Amino Acid, Jose F. Cerda

New Synthetic Approaches Toward Pentacyclo[4.3.0.02,4.03,8.05,7]non-4-ene, Mark A. Forman

Facile and Selective Aliphatic C-H Bond Activation at Ambient Temperatures Initiated by Cp*W(NO)(CH2CMe3)(η3-CH2CHCHMe), Peter Michael Graham

Oxidatively Induced Insertion of NO into a Metal-Carbon Bond, Peter Michael Graham

Reactivity of Cp*Mo(NO)(=CHCMe3) with Olefins and Dienes: C-H Activation Reactions of Molybdenacyclobutanes, Peter Michael Graham

Tungsten-Promoted Diels-Alder Cycloaddition of Pyridines: Dearomatization of 2,6-Dimethoxypyridine Generates a Potent 2-Azadiene Synthon, Peter Michael Graham

Role of conserved Fa-helix residues in the native fold and stability, Mark F. Reynolds

Role of Conserved Heme Domain Residues in the Oxygen Sensing Mechanism of FixL from S. meliloti., Mark F. Reynolds

The Role of Conserved Proximal Residues in the Heme-Based Oxygen Sensor FixL from S. meliloti., Mark F. Reynolds

Submissions from 2006

Reversible Binding of Heme to, Mark F. Reynolds

Submissions from 2005

Evaluating the Sediments of the Great Lakes as Long Term Sink for the 129I Released During the Nuclear Activities of the 1960s and 1970s, Usha Rao

The role of histidine 200 in MndD, the Mn(II)-dependent, Mark F. Reynolds

Submissions from 2004

Factors Influencing the Global Distribution of the 129I in the Environment: A Look at the Iodine Cycle in Surface Reservoirs, Usha Rao

Submissions from 2003

Electronic Absorption Spectra of Neutral Perylene (C20H12), Terrylene (C30H16), and Quaterrylene (C40H20) and Their Positive and Negative Ions: Ne Matrix-Isolation Spectroscopy and Time-Dependent Density Functional Theory Calculations, Thomas M. Halasinski

A Comparison of the Coordination Preferences of Zn, Co, and Cd(II) with the Heteriscorpionate Ligand 92-Hydroxy-3-tert-butyl-methylphenyl)bis(3,5-dimenthylpyrazolyl)methane, Brian S. Hammes

Bio-inspired Design of Tripodal Ligand Systems: Controlling the Primary and Secondary Coordination Sphere in Metal Complexes, Brian S. Hammes

Donor Atom Dependent Geometric Isomers in Mononuclear Oxo-Molybdenum(V) Complexes: Implications for Coordinated Endogenous Ligation in Molydbeonzymes, Brian S. Hammes

Synthesis and Characterization of Several Zinc(II) Complexes Containing the Bulky Hteriscorpionate Ligand Bis(5-tert-butyl-3-nethylpyrazol-2-yl)acetate: Relevance to the Resting State of the Zinc(II) Enzymes Thermolysin and Carboxypeptidase A, Brian S. Hammes

129 I and Total Iodine Depth Profiles in the Bottom Sedimenta of Lake Ontario: Tracking Emissions from Nuclear Fuel Reprocessing and Nucelar Weapon Testing, Usha Rao

Haem Can Bind to and Inhibit Mammalian Calcium-Dependents Slo 1 BK Channels, Mark F. Reynolds

Spectroscopic Studies of Fe-Substituted Mn-Dependent MndD, an Extradiol-Cleaving Catechol Dioxygenase from Arthrobacter Globiformis CM-2, Reveal a Blue-Green Enzyme with an Inactive Fe-Fatcholate Active Site, Mark F. Reynolds

Reductive Dissolution of Goethite and the Subsequent Transformation of 4-Cyanonitrobenzene: Role of Ascorbic Acid and pH, Jean M. Smolen

Role of Ascorbic Acid and Cysteine in the Reductive Dissolution of Iron-Rich Minerals and the Subsequent Transformation of 4-Cyanonitribenzene, Jean M. Smolen

The Role of Cysteine in the Reductive Dissolution of Ferric Oxides and the Subsequent Transformation of 4-Cyanonitrobenzene, Jean M. Smolen

Submissions from 2002

An Overview of Time Domain Spectroscopy, John G. Berberian

Spectroscopy of Large PAHs. Laboratory Studies and Comparison to Diffuse the Interstellar Bands, Thomas M. Halasinski

Spectroscopy of Large PAHs. Laboratory Studies and Comparison to the Diffuse Interstellar Bands, Thomas M. Halasinski

Guest Preorganization: An Alternative "Bioinspired" Paradigm in Host-Guest Chemistry, Brian S. Hammes

Metal Complexes of 3-Carboxyethyl Substituted Tripyrazolyborates: Interactions with Ester Carbonyl Oxygens, Brian S. Hammes

Modulating the Reduction Potential of Mononuclear Cobalt(II) Complexes via Selective Deprotonation of Tris[2-benzimidazolyl)methyl]amine, Brian S. Hammes

Synthesis and Characterization of Several Zinc (II) Complexes Containing the Bulky Heteroscorpionate Ligand Bis (5-tert-butyl-3-methylpyrazol-2-yl) Acetate: Relevance to the Resting State of the Zinc (II) Enzymes Thermolysin and Carboxypeptidase A, Brian S. Hammes

Synthesis, Characterization, Electrochemistry, Electronic Structure, and Isomerization of Mononuclear Oxo-Molybdenum(V) Compexes: The Serine Gate Hypothesis in the Function of DMSO Reductases, Brian S. Hammes

Zinc Complexes of Hydrogen Bond Accepting Ester Substituted Trispyrazolyborates, Brian S. Hammes

Alternative Solvent Extraction Systems to Replace Carbon Tetrachloride in Iodine Extraction, Usha Rao

Tracing the History of Nuclear Releases: Determination of Iodine-129 in Tree Rings, Usha Rao

4-Nictrocatechol as a Probe of a Mn (II)-Dependent Extradiol-Cleaving Catechol Dioxygenase (MndD). A Comparison with Relevant Fe (II) and Mn (II) Model Complexes, Mark F. Reynolds

Activation of Soluble Guanylyl Cyclase by Four-Coordinate Metallopophyrins: Evidence for a Role for Pophyrins Conformation, Mark F. Reynolds

Site-Directed Mutagenesis Studies of Conserved Second Coordination Sphere Residues in the Manganese-Dependant 3,4-Dihydroxyphenlacetate 2,3-Dioxygenases from Arthrobacter Globiformis Strain CM-2 Suggest the Importance of H200 in Stabilizing the Metal Bound Superoxide in the Extradiol Cleavage Mechanism, Mark F. Reynolds

The Effect of Subsituents on the Phenyl Portion of the Imido Ligand on the Structure and Properties of Molybdenum (VI) Imido Complexes, Mark F. Reynolds

The Role of Ascorbic Acid in the Reductive Dissolution of Goethite and the Subsequent Reductive Transformation of 4-Cyanonitrobenzene (4CNB), Jean M. Smolen

Submissions from 2001

Geometric Control of Reduction Potential in Oxomolybdenum Centers: Implications to the Serine Coordination in DMSO Reductase, Brian S. Hammes

Hydrogen-Bonding Cavities about Metal Ions: Synthesis, Structure, and Physical Properties for a Series of Monomeric M-OH Complexes Derived from Water, Brian S. Hammes

Methylation of (2-Methylethanethiol-bis-3,5-dimethylpyrazolyl)methane Zinc Complexes and Coordination of the Resulting Thioether: Relevance to Zinc-containing Alkyl Transfer Enzymes, Brian S. Hammes

New H-bond Accepting Trispyrazolylborates: Stabilization of Metal Aquo Species, Brian S. Hammes

The Methylation of Zinc Bound Thiolates: Relevance of Thioether Ligands in Zinco Containing Alkyl Transfer Enzymes, Brian S. Hammes

Mechanism in Activation of Soluble Guanylate Cyclase by NO: Allosteric Regulation Through Changes in Heme Coordination Geometry, Mark F. Reynolds

Submissions from 2000

Electronic Absorption Spectra of Neutral Pentacene (C22H14) and Its Positive and Negative Ions in Ne, Ar, and Kr Matrices, Thomas M. Halasinski

Alkyl Group Transfer to Pseudotetrahedral Zinc Thiolate Complexes Containing N2O and N2S Heteroscorpionate Ligands: Kinetics and Biological Relevance, Brian S. Hammes

Hydrogen Bonding in Metal Oxo Complexes: Synthesis and Structure of a Monomeric Manganese(III)-Oxo Complex, Brian S. Hammes

Methylation of (2-Methylethanethiol-bis-3,5-dimethylpyrazolyl)methane Zinc Complexes and Coordination of the Resulting Thioether: Relevance to Zinc-containing Alkyl Transfer Enzymes, Brian S. Hammes

Structure and Physical Properties of Several Pseudotetrahedral Zinc Complexes Containing a New Alkyl Thiolate Heteroscorpionate Ligand, Brian S. Hammes